https://pchome.megatime.com.tw 提供台股、大盤動態、個股股價當日行情即時排行、盤勢分析、股市公告、即時新聞、投資等資訊 https://pchome.megatime.com.tw/news/cat1/20260803/17856960002967041003.html Mon, 03 Aug 2026 02:40:00 +0800 https://pchome.megatime.com.tw/news/cat1/20260803/17856960002967041003.html AI,三大法人,中石化,伺服器,力積電,加權指數 卡優新聞 https://pchome.megatime.com.tw/news/cat1/20260803/9700001799202608032.html Mon, 03 Aug 2026 00:06:29 +0800 https://pchome.megatime.com.tw/news/cat1/20260803/9700001799202608032.html 公開資訊觀測站 https://pchome.megatime.com.tw/news/cat1/20260802/9700004128202608024.html 5 cm2 (52人): 完全癒合率73.9%，比較輔料對照組37.5% (P =0.012) c.HbA1c > 7% (69人): 完全癒合率75.0%，比較輔料對照組41.9% (P =0.010) d.BMI≧25 (46人): 完全癒合率70.8%，比較輔料對照組37.5% (P =0.037) e.潰瘍持續時間≧3個月(71人): 完全癒合率63.9%，比較輔料對照組37.0% (P =0.035) f.有截肢病史(50人) : 完全癒合率76.2%，比較輔料對照組39.1% (P =0.013) g.血管病變 (91人): 完全癒合率81.8%，比較輔料對照組50.0% (P =0.002) h.神經病變 (112人): 完全癒合率74.5%，比較輔料對照組43.5% (P =0.001) 重要次要療效指標： 在16週的治療期內，由研究者評估目標潰瘍達到完全癒合的時間。 ON101組於達到完全癒合的時間，優於輔料對照組 (P= 0.021)， 達到統計顯著差異。 探索性指標： 評估治療期達到傷口完全癒合的受試者，在追蹤期內目標潰瘍的復發率。 兩組復發率相當，無統計顯著差異。 安全性評估： 於治療期間觀察到與藥物可能相關之不良事件，ON101組有1人(1.6%)，輔料對 照組有4人(6.8%)，兩組無統計顯著差異。其中，有2人發生與藥物可能相關 之嚴重不良事件(SAE)，皆為輔料對照組。 (C)單一臨床試驗結果(包含主、次要評估指標之統計學P值及統計學上是否達 顯著意義)，並不足以充分反映未來新藥開發上市之成敗，投資人應審慎判斷 謹慎投資。(2)未通過目的事業主管機關許可者、各期人體臨床試驗(含期中分析)結果未達統計 上顯著意義或發生其他影響新藥研發之重大事件者，公司所面臨之風險及因應措 施：不適用。(3)已通過目的事業主管機關許可者、各期人體臨床試驗(含期中分析)結果達統計上 顯著意義或發生其他影響新藥研發之重大事件者，未來經營方向：不適用。(4)已投入之累積研發費用：考量未來市場行銷策略，為保障公司及投資人權益， 不公開揭露。6.將再進行之下一階段研發(請說明預計完成時間及預計應負擔之義務):(1)「速必一」(ON101)為中國大陸NMPA核准的第一個1.1類天然藥物新藥，核准適 應症為治療Wagner 1級糖尿病足部傷口潰瘍 (ON101在其他48個國家地區核准適應 症均為Wagner 1-5級)，並要求執行上市後兩階段臨床試驗 (ON101CLCT06)。試驗為 雙盲、輔料對照、隨機分配，收納較嚴重的Wagner 2級患者，第一階段120人試驗 結果，業經兩岸專家組成的IDMC(獨立數據監督委員會)一致同意，因ON101無安全 性疑慮且具有顯著臨床效益，建議無須執行第二階段試驗，以第一階段結果提前 終止試驗。(2)本試驗結果將遞交大陸藥品法規單位，申請在大陸擴大適應症，及停止後續 臨床試驗，至於是否通過，將視法規單位最終審查而定。(3)預計完成時間：視法規單位審查而定。(4)預計應負擔之義務：無。7.市場現況: 根據統計，中國成人糖尿病患者約2.33億人，糖尿病足潰瘍患者超過1,000萬人。 糖尿病足為糖尿病最嚴重且醫療負擔最高的慢性併發症之一，患者終身發生足部 潰瘍風險約二至三成，約其中20%面臨截肢風險，重大截肢後五年死亡率高達50%， 臨床存在高度未滿足醫療需求。 糖尿病足潰瘍造成沉重的醫療與社會經濟負擔，相關治療費用約占糖尿病整體醫療 支出的三分之一，主要來自住院治療、感染控制、清創、血管重建及截肢後長期照 護，對患者、家庭及醫療體系均造成重大負擔。8.其他應敘明事項(若事件發生或決議之主體係屬公開發行以上公司，本則重大訊息同時符合證券交易法施行細則第7條第8款所定對股東權益或證券價格有重大影響之事項): 本試驗為遵循美國FDA發佈的《慢性皮膚潰瘍與燒傷傷口治療產品開發指南》設計的隨 機、雙盲、平行組、輔料對照的研究，試驗設計嚴謹，臨床結果IRC(獨立審評委員會) 盲性評估臨床療效達一致性，為1997年美國FDA核發唯一的治療糖尿病足潰瘍藥物 上市迄今，唯一試驗達標的產品。9.新藥開發時程長、投入經費高且未保證一定能成功，此等可能使投資面臨風險，投 資人應審慎判斷謹慎投資。:]]> Sun, 02 Aug 2026 20:28:05 +0800 https://pchome.megatime.com.tw/news/cat1/20260802/9700004128202608024.html 公開資訊觀測站 https://pchome.megatime.com.tw/news/cat1/20260802/9700004743202608021.html 5 cm2 (52人): 完全癒合率73.9%，比較輔料對照組37.5% (P =0.012) c.HbA1c > 7% (69人): 完全癒合率75.0%，比較輔料對照組41.9% (P =0.010) d.BMI≧25 (46人): 完全癒合率70.8%，比較輔料對照組37.5% (P =0.037) e.潰瘍持續時間≧3個月(71人): 完全癒合率63.9%，比較輔料對照組37.0% (P =0.035) f.有截肢病史(50人) : 完全癒合率76.2%，比較輔料對照組39.1% (P =0.013) g.血管病變 (91人): 完全癒合率81.8%，比較輔料對照組50.0% (P =0.002) h.神經病變 (112人): 完全癒合率74.5%，比較輔料對照組43.5% (P =0.001) 重要次要療效指標： 在16週的治療期內，由研究者評估目標潰瘍達到完全癒合的時間。 ON101組於達到完全癒合的時間，優於輔料對照組 (P =0.021) ，達到統計顯著 差異。 探索性指標： 評估治療期達到傷口完全癒合的受試者，在追蹤期內目標潰瘍的復發率。 兩組復發率相當，無統計顯著差異。 安全性評估： 於治療期間觀察到與藥物可能相關之不良事件，ON101組有1人(1.6%)，輔料對 照組有4人(6.8%)，兩組無統計顯著差異。其中，有2人發生與藥物可能相關之 嚴重不良事件(SAE)，皆為輔料對照組。 (C)單一臨床試驗結果(包含主、次要評估指標之統計學P值及統計學上是否達顯著 意義)，並不足以充分反映未來新藥開發上市之成敗，投資人應審慎判斷謹慎 投資。(2)未通過目的事業主管機關許可者、各期人體臨床試驗(含期中分析)結果未達統計上 顯著意義或發生其他影響新藥研發之重大事件者，公司所面臨之風險及因應措施： 不適用。(3)已通過目的事業主管機關許可者、各期人體臨床試驗(含期中分析)結果達統計上顯 著意義或發生其他影響新藥研發之重大事件者，未來經營方向：不適用。(4)已投入之累積研發費用：考量未來市場行銷策略，為保障公司及投資人權益，不公 開揭露。6.將再進行之下一階段研發(請說明預計完成時間及預計應負擔之義務):(1)「速必一」(ON101)為中國大陸NMPA核准的第一個1.1類天然藥物新藥，核准適應症 為治療Wagner 1級糖尿病足部傷口潰瘍 (ON101在其他48個國家地區核准適應症均 為Wagner 1-5級)，並要求執行上市後兩階段臨床試驗 (ON101CLCT06)。試驗為雙 盲、輔料對照、隨機分配，收納較嚴重的Wagner 2級患者，第一階段120人試驗結 果，業經兩岸專家組成的IDMC(獨立數據監督委員會)一致同意，因ON101無安全性 疑慮且具有顯著臨床效益，建議無須執行第二階段試驗，以第一階段結果提前終 止試驗。(2)因本項試驗設計嚴謹，TFDA認可為一項確證性試驗，已同意替代本公司原擬於美 國執行的三期臨床試驗 (計畫編號: ON101CLCT04)。(3)本試驗結果將遞交兩岸藥品法規單位，申請在大陸擴大適應症，及停止後續臨床 試驗；同時滿足台灣上市後試驗要求，至於是否通過，將視法規單位最終審查而 定。(4)預計完成時間：視法規單位審查而定。(5)預計應負擔之義務：無。7.市場現況: 根據統計，中國成人糖尿病患者約2.33億人，糖尿病足潰瘍患者超過1,000萬人。 糖尿病足為糖尿病最嚴重且醫療負擔最高的慢性併發症之一，患者終身發生足部 潰瘍風險約二至三成，其中20%面臨截肢風險，重大截肢後五年死亡率高達50% ，臨床存在高度未滿足醫療需求。 糖尿病足潰瘍造成沉重的醫療與社會經濟負擔，相關治療費用約占糖尿病整體醫 療支出的三分之一，主要來自住院治療、感染控制、清創、血管重建及截肢後長 期照護，對患者、家庭及醫療體系均造成重大負擔。8.其他應敘明事項(若事件發生或決議之主體係屬公開發行以上公司，本則重大訊息同時符合證券交易法施行細則第7條第8款所定對股東權益或證券價格有重大影響之事項):本試驗為遵循美國FDA發佈的《慢性皮膚潰瘍與燒傷傷口治療產品開發指南》設計的隨機、雙盲、平行組、輔料對照的研究，試驗設計嚴謹，臨床結果IRC(獨立審評委員會)盲性評估臨床療效達一致性，為1997年美國FDA核發唯一的治療糖尿病足潰瘍藥物上市迄今，唯一試驗達標的產品。9.新藥開發時程長、投入經費高且未保證一定能成功，此等可能使投資面臨風險，投 資人應審慎判斷謹慎投資。:]]> Sun, 02 Aug 2026 19:13:23 +0800 https://pchome.megatime.com.tw/news/cat1/20260802/9700004743202608021.html 公開資訊觀測站 https://pchome.megatime.com.tw/news/cat1/20260802/78566293291409207003.html Sun, 02 Aug 2026 17:28:52 +0800 https://pchome.megatime.com.tw/news/cat1/20260802/78566293291409207003.html 00878,00881,AI,AI伺服器,ETF,IC設計 nownews https://pchome.megatime.com.tw/news/cat1/20260802/78565980064384338005.html Sun, 02 Aug 2026 16:36:40 +0800 https://pchome.megatime.com.tw/news/cat1/20260802/78565980064384338005.html AI,AI應用,AWS,互動,冠軍,半導體 黃仁杰 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https://pchome.megatime.com.tw/news/cat1/20260802/78563887278113207003.html Sun, 02 Aug 2026 10:47:52 +0800 https://pchome.megatime.com.tw/news/cat1/20260802/78563887278113207003.html 半導體,台電,電力,高雄,高雄市 nownews https://pchome.megatime.com.tw/news/cat1/20260802/78563583122341316003.html Sun, 02 Aug 2026 09:57:11 +0800 https://pchome.megatime.com.tw/news/cat1/20260802/78563583122341316003.html 2028,Samsung,三星,力士,半導體,南韓 周刊王CTWANT https://pchome.megatime.com.tw/news/cat1/20260802/9700004305202608021.html Sun, 02 Aug 2026 09:46:48 +0800 https://pchome.megatime.com.tw/news/cat1/20260802/9700004305202608021.html 公開資訊觀測站 https://pchome.megatime.com.tw/news/cat1/20260802/78563384285458207003.html Sun, 02 Aug 2026 09:24:02 +0800 https://pchome.megatime.com.tw/news/cat1/20260802/78563384285458207003.html AI,AI伺服器,EPS,ETF,PCB,主動式ETF nownews https://pchome.megatime.com.tw/news/cat1/20260802/9700006655202608021.html Sun, 02 Aug 2026 09:11:07 +0800 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https://pchome.megatime.com.tw/news/cat1/20260801/9700007731202608011.html 公開資訊觀測站 https://pchome.megatime.com.tw/news/cat1/20260801/9700002402202608011.html Sat, 01 Aug 2026 18:22:56 +0800 https://pchome.megatime.com.tw/news/cat1/20260801/9700002402202608011.html 公開資訊觀測站 https://pchome.megatime.com.tw/news/cat1/20260801/9700006294202608011.html Sat, 01 Aug 2026 17:57:01 +0800 https://pchome.megatime.com.tw/news/cat1/20260801/9700006294202608011.html 公開資訊觀測站 https://pchome.megatime.com.tw/news/cat1/20260801/78557757521480227001.html Sat, 01 Aug 2026 17:46:15 +0800 https://pchome.megatime.com.tw/news/cat1/20260801/78557757521480227001.html 下屬,中聯,主管,力銘,南僑,台積電 張孝義 https://pchome.megatime.com.tw/news/cat1/20260801/78557600719956312101.html Sat, 01 Aug 2026 17:20:07 +0800 https://pchome.megatime.com.tw/news/cat1/20260801/78557600719956312101.html Q3,主管,二手,健保,全聯,全聯福利中心 樂屋網 https://pchome.megatime.com.tw/news/cat1/20260801/78557600551261312101.html Sat, 01 Aug 2026 17:20:05 +0800 https://pchome.megatime.com.tw/news/cat1/20260801/78557600551261312101.html Q3,二手,全台,全國,利空,台中市 樂屋網 https://pchome.megatime.com.tw/news/cat1/20260801/78557600365468312101.html 60% ~ 70%）： 已觸及大多數銀行之風控天花板，原則上難以通過原定額度審核，常面臨退件或要求強制增加符合條件之連帶保證人。三、 影響 DIR 的隱形殺手：信貸、車貸與信用卡分期如何吃掉房貸額度許多申貸人在規劃買房時，常忽略名下小額債務對 DIR 分子的強烈放大效應。由於信用貸款與汽車貸款的還款期限較短（信貸多為 5~7 年，車貸多為 3~5 年），其每月應繳本息（月付金）佔比極高，對 DIR 的破壞力遠超想像。【實務精算案例】假設申貸人小明，平均月收入為 新台幣 8 萬元，名下無任何其他資產證明。銀行設定之 DIR 警戒上限為 60%（即每月債務總支出不得超過 80,000 x 60% = 48,000 元）。情境 A：小明名下完全無其他債務可承受之最大每月房貸月付金 = 48,000 元。以房貸利率 2.2%、貸款年限 30 年（本息平均攤還）試算：小明最高約可申貸 1,250 萬元 的房貸額度。情境 B：小明名下有一筆 50 萬元的個人信用貸款（年限 5 年，月付金約 9,500 元），且信用卡每月有 5,000 元零利率分期既有每月固定債務支出 = 9,500 + 5,000 = 14,500 元。剩餘可分配給新房貸之月付金天花板 = 48,000 - 14,500 = 33,500 元。同樣以 2.2% 利率、30 年期試算：小明可申貸之房貸額度大幅縮減至 870 萬元。結果分析： 僅僅 50 萬元的信貸與 5,000 元的信用卡分期，因為拉高了 DIR 的分子，直接導致小明的房屋貸款可貸額度蒸發了將近 380 萬元。【不同債務型態對 DIR 及房貸額度之壓制效果對照表】既有債務類型常態貸款年限每月應繳本息金額（以借款金額估算）對 DIR 分子之拉升幅度對房貸可貸額度之排擠效果房屋貸款（擬申辦/既有）30 ~ 40 年約 3,800 ~ 4,000 元(每貸款 100 萬估算)低（年限長，月付金壓低）基於房屋殘值與收支比進行核算個人信用貸款5 ~ 7 年約 7,000 ~ 9,500 元(每貸款 50 萬估算)極高（期數短，月付金比重高）嚴重壓縮額度。每多 1 萬元信貸月付金，約直接吃掉 250~260 萬的房貸額度汽車貸款 / 機車貸款3 ~ 5 年約 9,500 ~ 15,000 元 / 每五十萬極高（短期高月付金）強烈拉高負債比，顯著影響核貸成數信用卡預借現金 / 循環利息隨期結算視帳單最低應繳金額及高額利息而定極高（且嚴重扣減聯徵信用分數）銀行風控的紅線指標。極易引發銀行系統直接退件，屬於高違約風險戶信用卡零利率分期付款3 ~ 24 期依每期分期金額全額逐期納入中高（視未到期總金額而定）許多人忽視的隱形殺手，常累積過多月付金四、 首購族自救：如何在送件前優化 DIR？如果在買屋對保前，經過精算發現自身的 DIR 負債比已接近或超過銀行的風控警戒線，首購族可採取以下四招實務策略進行財務結構調校：策略 1：優先清償短年限小額債務（精準降低分子）在資金有限的情況下，清償債務的優先順序應以「月付金最高、期數最短」的債務為先。結清信用卡分期付款：在送件前 1 至 2 個月，將所有信用卡的未到期分期、預借現金一次全額清償，並停止使用分期功能。優先清償剩餘期數較短的個人信用貸款或車貸，並在清償後要求金融機構開立清償證明。送件時附上清償證明，銀行審查即可將該筆月付金自 DIR 分子中剔除。策略 2：提報完整且正規的收入憑證（擴大分母）分母越大，算出的 DIR 百分比就越低。許多受薪階級在送件時僅提供近 3 個月的薪轉存摺，容易忽視其他合法收入來源：提供完整年度扣繳憑單： 扣繳憑單通常包含全年的年終獎金、績效獎金與三節獎金，能真實反映個人年度總獲利能力。（註：銀行審核非固定獎金時，通常會打 6 至 8 折認定，或採取近兩年平均值計算，送件時可多準備兩年份以備不時之需。）列入經常性給與項目： 若薪資結構中包含固定發放的伙食津貼、職務加給、固定加班費等，應向公司人事部門申請薪資明細證明，確保銀行列入經常性收入計算。策略 3：拉長房貸年限以壓低單月本息負擔（壓低分子）申辦 40 年期房貸相較於 20 年或 30 年期房貸，雖然總利息支出較高，但能顯著降低「每月的本息攤還金額」：降低月付金壓力：當每月房貸負擔金額下降，DIR 計算公式中的分子隨之縮小，能將負債比壓回安全的核貸區。【實務申辦紅線】：40 年期房貸並非人人可辦。銀行審核設有「借款人年齡 + 貸款年限 ≤ 80」以及「屋齡 + 貸款年限 ≤ 50 至 60」的剛性限制。因此，此策略通常僅限於「35 歲以下、且購買新成屋」的年輕首購族。若不符資格，折衷方案是改爭取 3 年至 5 年的房貸寬限期（期內只付利息不還本金），在對保初期同樣能有效壓低 DTI 分子。策略 4：依法補強資產證明或增加連帶保證人若個人經常性收入受限，可向銀行提出其他輔助資產以證明還款無虞：資產證明： 提報名下長期持有的台美股股票市值證明、定期存款單、投資型保險保單價值準備金等。部分銀行可依特定比例折算為輔助收入。增加連帶保證人： 依據《銀行法》第 12 條之 1 規定，銀行在已取得足額擔保（即房屋抵押）時，不得強制要求提供連帶保證人。但在實務上，若申辦人因 DIR 負債比不足而卡關，申貸人可以「主動提供」具備優質、穩定收入來源的二等親內親屬（如父母、子女）或配偶擔任「一般保證人」。如此一來，銀行審查時便能將保證人的收入合併計入分母共同計算，大幅拉高過件率，這是突破負債比限制最快、最有效的方法。五、 核心 FAQ（常見問題解答）Q1：我平時信用卡都按時全額繳清、從不遲繳，但每月刷卡金額高達十幾萬，這樣會影響 DIR 嗎？解答： 基本上不影響 DIR 分子，但可能影響流動資金審查。若信用卡每月皆在繳款截止日前全額繳清，未產生任何循環利息或未到期分期付款，銀行在計算 DIR 時，不會將該月刷卡消費金額列為「固定月付款債務」。然而，若送件時存摺餘額因刷卡扣款過多而過低，銀行仍會關切申貸人是否具備足夠的緊急預備金與交屋自備款。Q2：股票股利、基金配息可以算在 DIR 的收入分母裡面嗎？解答： 可以，但銀行會進行折扣或設有採納門檻。金融機構認定股票現金股利或基金配息為「變動性投資收入」。由於市場價格與配息政策具波動性，銀行通常要求申貸人提供連續 1 至 2 年以上的完整獲利憑證（如綜合所得稅核定清單、股利發放通知書或證券劃撥集保帳戶存摺）。審查時，銀行為了防範景氣波動風險，多會採取「近 2 年平均金額再打 7 折至 8 折」的方式，保守列入 DIR 的分母（收入）中計算。Q3：學貸（青年學生發起之就學貸款）會吃掉我的房貸 DIR 額度嗎？解答： 會的，但影響相對溫和。就學貸款在金融機構認定中，依然屬於「個人名下的法定債務」，因此每個月必須攤還的本息金額，會如實計入 DIR 的分子（負債）中。不過，由於學貸具備利率低、還款年限長等政策優惠特性，每月的月付金通常較低。此外，銀行對學貸的風險排斥感，遠低於一般的個人消費性信用貸款。只要您過去持續按時履約、從未遲繳，學貸對 DIR 的衝擊都在可控範圍內，對整體核貸率的影響也相對輕微。六、 結論：以理性的風控紀律，穩健規劃購屋融資總體而言，房屋貸款的申請本質上是一場金融機構風控數學題。信用分數僅是檢驗申貸人道德風險的門檻，而 DIR 負債比才是決定資金能否順利撥付的物理防線。在決定簽約購屋、下斡旋之前，請務必將眼光從感性的房價漲跌與信用分數收回來，回歸理性的財務算式：精算個人與家庭的淨每月經常性收入（分母）。清點名下所有信貸、車貸與分期付款之月付金（分子）。確保擬申辦之房貸本息加上既有債務後，總 DIR 控制在 50% 至 60% 的黃金安全水位。提前於對保前 3 至 6 個月進行債務清理與資產整理，讓理性的財務大數據走在申貸流程的前面，才能在買房長徵中精準避開拒貸風險，成功為自己與家人護航安居夢想。更多好屋等你挖掘台北市買房找屋新北市買房找屋桃園市買房找屋新竹市買房找屋台中市買房找屋台南市買房找屋高雄市買房找屋延伸閱讀▌豪宅定義、豪宅線全解析！高價住宅定義與豪宅稅制變動▌青年首購貸款攻略：目前房貸利率最低銀行？首購寬限期、各銀行產品總整理▌2026租屋/售屋刊登網站推薦：哪家費用最省？樂屋網3大核心刊登方案全攻略▌買房要準備多少錢？自備款、隱藏成本與貸款總費用計算全攻略▌中古屋驗屋怎麼驗？網曝：預防勝於治療，不是等交屋才做►議價要精準，周邊成交行情一網打盡，快試試樂屋網實價登錄► 點我下載「樂屋網 APP」，搶先體驗個人化專屬功能文章來源：房貸過件關鍵不是聯徵分數！銀行 DIR 負債比計算全攻略：為什麼信用滿分照樣被拒貸？全台租屋一鍵查詢，找到理想租處實價地圖即時查，鄰近成交價一目了然實價登錄一鍵查詢，做對買賣決策]]> Sat, 01 Aug 2026 17:20:03 +0800 https://pchome.megatime.com.tw/news/cat1/20260801/78557600365468312101.html 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